Melatonin And Its Diuretic Effects

Melatonin is a natural hormone that is useful in regulating the sleep and waking cycles. Although, this is found naturally in the body, this is also obtainable synthetically in the form of a pill. There are several people who take melatonin due to its sleep-inducing and calming properties. If you are taking diuretics, these can disrupt the production of melatonin in the body. This also applies to melatonin in pill form. Unwanted complication can be prevented if you know the effects of diuretics in melatonin.

The pineal gland located in the brain produces melatonin and this is released into the bloodstream. Usually, the hormone is formed in darkness and helps the body to sleep due to its calming effect. This aids in regulating the circadian rhythms as well as the sleep cycle. Also, melatonin has antioxidant properties so that it is able to protect the nuclear and mitochondrial DNA. Laboratories create synthetic melatonin and anyone can avail this hormone in the form of a pill as a supplement. According to MedlinePlus, this is frequently taken to effectively induce sleep. Most people take melatonin for a variety of reasons also. These include migraines, ringing in the ears, chronic fatigue syndrome, epilepsy, for menopause, depression, Alzheimer’s disease, for birth control, fibromyalgia, as an anti-aging agent, irritable bowel syndrome, a movement disorder termed as tardive dyskinesia and bone loss or osteoporosis.


Melatonin is not regulated or approved by the Food and Drug Administration of America although; this is readily available over the counter. Hence, no standard guidelines for the dosage and ingredients of melatonin are available. More research has to be done regarding its long-term effects as well as drug interactions with melatonin. However, the Mayo Clinic recommends that the supplement should not be taken for more than two months. Melatonin can lead to drowsiness that is why, this should not be used by people who are operating heavy machinery or driving. When you buy melatonin, opt for the synthetic varieties since melatonin from animals can have viruses or other contaminants.

Diuretics and Melatonin

Diuretics promote urination and are used in treating a variety of conditions such as IBD, heart disorders, constipation and edema which is characterized by buildup of fluids inside the body. Several diuretics like Lasix or furosemide can disrupt with the production of melatonin and reduce the effectiveness of melatonin supplements. MedlinePlus indicates that diuretics are not on the list that will cause complications with melatonin. But more research has to be conducted on this matter. If you are using a diuretic and melatonin, it is better to talk with your physician regarding the potential side effects.

The side effects of melatonin include nightmares, pain in the stomach, headaches, sleepiness during daytime, drowsiness, sleepwalking and confusion. Even if melatonin does not produce a diuretic effect, there is a possibility that you will suffer from increase pain in the stomach when you take it if you have IBS. If you are using a diuretic to reduce your blood pressure or get relief from a heart condition, or perhaps due to an immune disorder, you need to consult with your doctor before taking melatonin. Take note that melatonin should not be used as an alternative for medical treatment. Visit the doctor’s office if you happen to have an ongoing problem or condition.

This entry was posted in Food Supplements. Bookmark the permalink.

Comments are closed.